Synthesis of optically active phenylglycine derivatives from Ss-(+)-N-(benzylidene)-p-toluenesulfinamide by using Lewis acids and tert-amines

被引：27

作者：

Nemoto, H ^{[1
]}

Ma, RJ ^{[1
]}

Moriguchi, H ^{[1
]}

Suzuki, I ^{[1
]}

Shibuya, M ^{[1
]}

机构：

[1] Univ Tokushima, Fac Pharmaceut Sci, Tokushima 7708505, Japan

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2000年 / 611卷 / 1-2期

关键词：

acyl cyanides; asymmetric synthesis; phenylglycine; amino acids and peptides; peptides; sulfinimines; Lewis acids;

D O I：

10.1016/S0022-328X(00)00478-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Stereoselective synthesis of L- and D-phenylglycine derivatives was accomplished by the reaction of Ss-(+)-N-(benzylidene)-p-toluenesulfinamide with 2-(tert-butyldimethylsiloxy)malononitrile (H-MAC-TBS) in the presence of Lewis acids and tert-amines. (C) 2000 Published by Elsevier Science S.A. All rights reserved.

引用

页码：445 / 448

页数：4

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