Cloning and sequence of the gene encoding a novel cefetoxime-hydrolyzing β-lactamase (CTX-M-9) from Escherichia coli in Spain

被引：109

作者：

Sabaté, M

Tarragó, F

Navarro, F

Miró, E

Vergés, C

Barbé, J

Prats, G

机构：

[1] Hosp Santa Cruz & San Pablo, Dept Microbiol, E-08025 Barcelona, Spain

[2] Univ Autonoma Barcelona, Dept Genet & Microbiol, Bellaterra 08193, Spain

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2000年 / 44卷 / 07期

关键词：

D O I：

10.1128/AAC.44.7.1970-1973.2000

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A new CTX-M-type beta-lactamase (CTX-M-9) has been cloned from a clinical cefotaxime-resistant Escherichia coli strain. Despite the close identity that exists between the CTX-M-9 and Toho-2 beta-lactamases (88%), the 35 amino acids located between residues Ala-185 and Ala-219 are totally different in both enzymes. Outside of this region there are only six amino acids substitutions between both proteins.

引用

页码：1970 / 1973

页数：4