The vasculoprotective effects of flavonoid-rich cocoa and chocolate

被引：33

作者：

Engler, MB ^{[1
]}

Engler, MM ^{[1
]}

机构：

[1] Univ Calif San Francisco, Dept Physiol Nursing, Lab Cardiovasc Physiol, San Francisco, CA 94143 USA

来源：

NUTRITION RESEARCH | 2004年 / 24卷 / 09期

关键词：

endothelial; chocolate; epicatechin; cocoa; oxidation; inflammation;

D O I：

10.1016/j.nutres.2004.05.001

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

The current evidence on the vasculoprotective effects of flavonoid-rich cocoa and chocolate is reviewed. Cocoa flavonoids are derived from the cacao bean, found in the fruit pod of the cacao tree, Theobroma cacao. There is growing evidence that dietary supplementation with flavonoid-rich cocoa and chocolate may be cardioprotective because of their interference in many pathophysiological mechanisms associated with atherosclerosis. Possible beneficial effects by cocoa flavonoids include: antioxidant properties, improvement in endothelial function, blood pressure lowering, decreased platelet activation and function, and modulation of immune function and inflammation. Larger, long-term clinical trials investigating the potential beneficial effects of purified flavonoids and food sources rich in flavonoids, including cocoa and chocolate, are certainly warranted. (C) 2004 Elsevier Inc. All rights reserved.

引用

页码：695 / 706

页数：12

共 44 条

[21] Epicatechin, catechin, and dimeric procyanidins inhibit PMA-induced NF-κB activation at multiple steps in Jurkat T cells [J].