Ruthenium-catalyzed [2+2] cycloadditions of 2-substituted norbornenes

被引：69

作者：

Jordan, RW ^{[1
]}

Tam, W ^{[1
]}

机构：

[1] Univ Guelph, Guelph Waterloo Ctr Grad Work Chem & Biochem, Dept Chem & Biochem, Guelph, ON N1G 2W1, Canada

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 19期

关键词：

D O I：

10.1021/ol006397t

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

GRAPHICS The studies of remote substituent effects in controlling regio- and stereoselectivities in chemical reactions provide important information in understanding long-range stereoelectronic effects. The effect of remote substituents on ruthenium-catalyzed [2 + 2] cycloadditions of 2-substituted norbornenes has been investigated. The cycloadditions occurred at room temperature in excellent yields, and regioselectivities of 1.2:1 to 7.5:1 were observed with various P-substituted norbornenes.

引用

页码：3031 / 3034

页数：4

共 21 条

[11] Electronic control of facial selection in additions to sterically unbiased ketones and olefins [J].