Inhibition of mitochondrial lipid peroxidation by bakuchiol, a meroterpene from Psoralea corylifolia

被引：49

作者：

Haraguchi, H

Inoue, J

Tamura, Y

Mizutani, K

机构：

[1] Fukuyama Univ, Fac Engn, Fukuyama, Hiroshima 7290292, Japan

[2] Maruzen Pharmaceut Co Ltd, Biol & Chem Lab, Fukuyama, Hiroshima, Japan

来源：

PLANTA MEDICA | 2000年 / 66卷 / 06期

关键词：

D O I：

10.1055/s-2000-8605

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Bakuchiol, a meroterpene isolated from Psoralea corylifolia, prevented mitochondrial lipid peroxidation. Inhibition of oxygen consumption originating in lipid peroxidation was time-dependent. Bakuchiol protected mitochondrial respiratory enzyme activities against both NADPH-dependent and dihydroxyfumarate-induced peroxidation injury. Bakuchiol was shown to be effective to protect mitochondrial functions against oxidative stress.

引用

收藏

页码：569 / 571

页数：3

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