Cellular studies of auditory hair cell regeneration in birds

被引：78

作者：

Stone, JS

Rubel, EW

机构：

[1] Univ Washington, Virginia Merrill Bloedel Hearing Res Ctr, CHDD CD 176, Sch Med, Seattle, WA 98195 USA

[2] Univ Washington, Dept Otolaryngol, Sch Med, Seattle, WA 98195 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2000年 / 97卷 / 22期

关键词：

supporting cell; avian; basilar papilla;

D O I：

10.1073/pnas.97.22.11714

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A decade ago it was discovered that mature birds are able to regenerate hair cells, the receptors for auditory perception. This surprising finding generated hope in the field of auditory neuroscience that new hair cells someday may be coaxed to form in another class of warm-blooded vertebrates, mammals. We have made considerable progress toward understanding some cellular and molecular events that lead to hair cell regeneration in birds. This review discusses our current understanding of avian hair cell regeneration, with some comparisons to other vertebrate classes and other regenerative systems.

引用

页码：11714 / 11721

页数：8

共 169 条

[51] BASE-TO-APEX GRADIENT OF CELL-PROLIFERATION IN THE CHICK COCHLEA FOLLOWING KANAMYCIN-INDUCED HAIR CELL LOSS [J].