Oxetane synthesis via cyclisation of aryl sulfonate esters on polystyrene and PEG polymeric supports

被引：14

作者：

Behrendt, JM

Bala, K

Golding, P

Hailes, HC

机构：

[1] UCL, Dept Chem, London WC1H 0AJ, England

[2] AWE, Reading RG7 4PR, Berks, England

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 04期

关键词：

oxetanes; solid-phase reactions; PEG supported reactions;

D O I：

10.1016/j.tetlet.2004.11.138

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The addition of suitably protected pentaerythritols to polymer supported sulfonyl chloride with subsequent alkoxide formation and intramolecular cyclisation to generate oxetanes is described. This convenient method for the preparation of oxetanes has several advantages over analogous solution phase reactions and the methodology is extended to the preparation and use of a novel PEG-sulfonyl chloride. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：643 / 645

页数：3

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