Drinking pattern and socio-cultural aspects on immune response: an overview

被引:19
作者
Romeo, Javier [1 ]
Warnberg, Julia [1 ,2 ,3 ]
Marcos, Ascension [1 ]
机构
[1] CSIC, Inst Frio Spanish Natl Res Council, Inst Food Sci Technol & Nutr ICTAN, Immunonutr Res Grp,Dept Metab & Nutr, Madrid, Spain
[2] Univ Navarra, Dept Prevent Med & Publ Hlth, E-31080 Pamplona, Spain
[3] Univ Malaga, Dept Prevent Med & Publ Hlth, E-29071 Malaga, Spain
关键词
Alcohol; Immune response; Drinking pattern; Social drinking; MODERATE ALCOHOL-CONSUMPTION; CORONARY-HEART-DISEASE; INFLAMMATORY RESPONSES; DENSITY-LIPOPROTEIN; POSSIBLE MECHANISM; SYSTEMIC MARKERS; BEER CONSUMPTION; AVERAGE VOLUME; HOST-DEFENSE; RED WINE;
D O I
10.1017/S0029665110001904
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Social acceptance of drinking involves social and cultural roles and has important implications for public health. Since extensive evidence indicates that alcohol possesses immunomodulatory properties, scientists have recently debated the influence of alcohol consumption on the immune response, particularly in countries where drinking in a social setting is a part of cultural identity. Experimental and clinical data support the conclusion that alcohol is a potent immunomodulator. While high alcohol consumption suppresses a wide range of immune responses, leading to an increased incidence of a number of infectious diseases, moderate alcohol consumption may have a beneficial impact on the immune system, compared to alcohol abuse or abstinence, most likely clue to the multiple components of polyphenol-rich alcoholic contributing to the protective effect seen for moderate alcohol consumption on CVD and the immune system. Despite this, the scientific literature appears to be concerned about the diseases associated with excessive drinking in some societies and cultures. Thus, the present review recognizes the importance to consider social and cultural aspects of drinking when examining the whole dimension of alcohol consumption (amount, beverage type, frequency and variability), in order to estimate global risk of consequences on host defence to better understand alcohol-related harm or benefit.
引用
收藏
页码:341 / 346
页数:6
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