Asymmetric hydrogenation of enol phosphinates by iridium catalysts having N,P ligands

被引：71

作者：

Cheruku, Pradeep ^{[1
]}

Gohil, Suresh ^{[1
]}

Andersson, Pher G. ^{[1
]}

机构：

[1] Dept Biochem & Organ Chem, SE-75123 Uppsala, Sweden

来源：

ORGANIC LETTERS | 2007年 / 9卷 / 09期

关键词：

D O I：

10.1021/ol070325l

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Enol phosphinates, which are structural analogues of enol acetates, have for the first time been employed as substrates for Ir-catalyzed asymmetric hydrogenation. A number of enol phosphinates have been synthesized and reduced successfully with up to and above 99% ee.

引用

页码：1659 / 1661

页数：3

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