Improved magnetization alignment schemes for spin-lock relaxation experiments

被引：27

作者：

Hansen, D. Flemming

Kay, Lewis E.

机构：

[1] Univ Toronto, Dept Med Genet, Toronto, ON M5S 1A8, Canada

[2] Univ Toronto, Dept Biochem & Chem, Toronto, ON M5S 1A8, Canada

来源：

JOURNAL OF BIOMOLECULAR NMR | 2007年 / 37卷 / 04期

基金：

加拿大自然科学与工程研究理事会;

关键词：

magnetization alignment; Spin-lock; R1 rho relaxation; off-resonance 90 degrees pulse;

D O I：

10.1007/s10858-006-9126-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A pair of pulse schemes that spin-lock magnetization efficiently are presented. The design of the sequences benefited from a particularly simple relation that is derived describing to first order the evolution of any magnetization component due to the application of an off-resonance 90 degrees pulse. The sequences are shown theoretically and experimentally to significantly outperform the 90 degrees-delay-90 degrees element that is often used in current applications. It is shown that alignment of magnetization to within 1 degrees of the effective field can be obtained over a bandwidth extending between [-omega(SL), omega(SL)], where omega(SL) is the strength of the spin-lock field using a simple scheme that is an order of magnitude shorter than an adiabatic pulse that might also be used for a similar purpose.

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页码：245 / 255

页数：11

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