Novel glycolipids based on cyclodextrins

被引：39

作者：

Moutard, S

Perly, B

Godé, P

Demailly, G

Djedaïni-Pilard, F

机构：

[1] Univ Picardie, Lab Glucides, F-80039 Amiens, France

[2] CEA Saclay, DSM DRECAM, Serv Chim Mol, F-91191 Gif Sur Yvette, France

来源：

JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY | 2002年 / 44卷 / 1-4期

关键词：

amphiphilic cyclodextrin; detergent properties; self-organization; synthesis;

D O I：

10.1023/A:1023014718447

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Novel amphiphilic cyclodextrins have been prepared by grafting a phospholipid on a modified cyclodextrin through a spacing arm to combine the selectivity in size of cyclodextrins and the transport properties of phospholipids. Synthesis and full characterization by NMR and mass spectrometry have been performed. The aggregation process in water has been characterized by light scattering, DSC and P-31 NMR. This compound appears to assemble into large objects and displays a very low CMC. The detergent properties of the phospholipidyl-cyclodextrins have been evaluated.

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页码：317 / 322

页数：6

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