The yin and yang of chromatin spatial organization

被引：33

作者：

Cope, Nathan F. ^{[1
]}

Fraser, Peter ^{[1
]}

Eskiw, Christopher H. ^{[1
]}

机构：

[1] Babraham Inst, Lab Chromatin & Gene Express, Cambridge CB22 3AT, England

来源：

GENOME BIOLOGY | 2010年 / 11卷 / 03期

基金：

英国医学研究理事会; 英国生物技术与生命科学研究理事会;

关键词：

X-CHROMOSOME INACTIVATION; POLYCOMB GROUP PROTEINS; ODORANT RECEPTOR GENES; LOCUS-CONTROL REGION; RNA-POLYMERASE-II; INTERCHROMOSOMAL ASSOCIATIONS; TRANSCRIPTION FACTORIES; NUCLEAR DOMAIN; BINDING-SITES; CTCF-BINDING;

D O I：

10.1186/gb-2010-11-3-204

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Spatial organization of the genome is non-random. Preferential chromatin interactions, both in cis and in trans and between transcriptionally active and silent regions, influence organization.

引用

页数：8

共 85 条

[1] Virus infection induces NF-κB-dependent interchromosomal associations mediating monoallelic IFN-β gene expression [J].

Apostolou, Effie ;

Thanos, Dimitris .

CELL, 2008, 134 (01) :85-96

[2] X-chromosome inactivation: Counting, choice and initiation [J].

Avner, P ;

Heard, E .

NATURE REVIEWS GENETICS, 2001, 2 (01) :59-67

[3] Inheritance of Polycomb-dependent chromosomal interactions in Drosophila [J].

Bantignies, F ;

Grimaud, C ;

Lavrov, S ;

Gabut, M ;

Cavalli, G .

GENES & DEVELOPMENT, 2003, 17 (19) :2406-2420

[4]

Bolland DJ, 2009, ADV EXP MED BIOL, V650, P59

[5] Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin [J].

Brown, KE ;

Guest, SS ;

Smale, ST ;

Hahm, K ;

Merkenschlager, M ;

Fisher, AG .

CELL, 1997, 91 (06) :845-854

[6] SILENCERS IN ABDOMINAL-B, A HOMEOTIC DROSOPHILA GENE [J].

BUSTURIA, A ;

BIENZ, M .

EMBO JOURNAL, 1993, 12 (04) :1415-1425

[7] The human transcriptome map:: Clustering of highly expressed genes in chromosomal domains [J].

Caron, H ;

van Schaik, B ;

van der Mee, M ;

Baas, F ;

Riggins, G ;

van Sluis, P ;

Hermus, MC ;

van Asperen, R ;

Boon, K ;

Voûte, PA ;

Heisterkamp, S ;

van Kampen, A ;

Versteeg, R .

SCIENCE, 2001, 291 (5507) :1289-+

[8] Long-range chromatin regulatory interactions in vivo [J].

Carter, D ;

Chakalova, L ;

Osborne, CS ;

Dai, YF ;

Fraser, P .

NATURE GENETICS, 2002, 32 (04) :623-626

[9] A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced [J].

Chaumeil, Julie ;

Le Baccon, Patricia ;

Wutz, Anton ;

Heard, Edith .

GENES & DEVELOPMENT, 2006, 20 (16) :2223-2237

[10] Integration of external signaling pathways with the core transcriptional network in embryonic stem cells [J].

Chen, Xi ;

Xu, Han ;

Yuan, Ping ;

Fang, Fang ;

Huss, Mikael ;

Vega, Vinsensius B. ;

Wong, Eleanor ;

Orlov, Yuriy L. ;

Zhang, Weiwei ;

Jiang, Jianming ;

Loh, Yuin-Han ;

Yeo, Hock Chuan ;

Yeo, Zhen Xuan ;

Narang, Vipin ;

Govindarajan, Kunde Ramamoorthy ;

Leong, Bernard ;

Shahab, Atif ;

Ruan, Yijun ;

Bourque, Guillaume ;

Sung, Wing-Kin ;

Clarke, Neil D. ;

Wei, Chia-Lin ;

Ng, Huck-Hui .

CELL, 2008, 133 (06) :1106-1117

← 1 2 3 4 5 6 7 8 9 →