Osteocyte messages from a bony tomb

被引：31

作者：

Bonewald, Lynda F. ^{[1
]}

机构：

[1] Univ Missouri, Sch Dent, Dept Oral Biol, Kansas City, MO 64108 USA

来源：

CELL METABOLISM | 2007年 / 5卷 / 06期

关键词：

D O I：

10.1016/j.cmet.2007.05.008

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Until recently, osteocytes have escaped the limelight, embedded within their cave-like lacunae in the mineralized matrix of bone. In this issue of Cell Metabolism, Tatsumi et al. (2007) present evidence that this "third bone cell" can send either inhibitory signals to osteoclasts to maintain bone mass with normal loading or stimulatory signals to osteoclasts to initiate bone loss upon immobilization, thereby playing an indispensable role in skeletal homeostasis.

引用

页码：410 / 411

页数：2

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