Invasive group B streptococcal disease in infants: a 19-year nationwide study. Serotype distribution, incidence and recurrent infection

被引：32

作者：

Ekelund, K ^{[1
]}

Konradsen, HB ^{[1
]}

机构：

[1] Statens Serum Inst, Dept Bacteriol Mycol & Parasitol, Streptococcus Unit, DK-2300 Copenhagen S, Denmark

来源：

EPIDEMIOLOGY AND INFECTION | 2004年 / 132卷 / 06期

关键词：

D O I：

10.1017/S0950268804002808

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

During the period 1984-2002, 472 cases of invasive group B streptococcal (GBS) disease in infants aged 0-90 days in Denmark were registered. The overall incidence was 0-4/1000 live births. Most infants (73%) had early-onset GBS infection with 53% registered within the first day. Serotype III predominated (59%) with other serotypes as follows: Ia (16%), Ib (8%), NT (7%), II (6%), other serotypes (5%). Recurrence of GBS infection was registered in six infants, and the interval with no antibiotic therapy varied from 2 to 39 days. The serotypes of the isolates obtained from first and second episodes were identical (serotype III in five, and serotype Ia in one infant). Paired isolates were indistinguishable by PFGE and antibiotic susceptibility testing. Invasive GBS infections in infants are still a problem in Denmark, and recurrent infections are registered in 1% of these infants.

引用

收藏

页码：1083 / 1090

页数：8

相关论文

共 41 条

[11] INFANT WITH 2 RELAPSES OF GROUP-B STREPTOCOCCAL SEPSIS DOCUMENTED BY DNA RESTRICTION ENZYME ANALYSIS [J].

DENNING, DW ;

BRESSACK, M ;

TROUP, NJ ;

TOMPKINS, LS .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1988, 7 (10) :729-732

[12] RELAPSE DURING PENICILLIN TREATMENT OF GROUP-B STREPTOCOCCAL MENINGITIS [J].

DORAND, RD ;

ADAMS, G .

JOURNAL OF PEDIATRICS, 1976, 89 (02) :188-190

[13] Emergence of invasive serotype VIII group B streptococcal infections in Denmark [J].

Ekelund, K ;

Slotved, HC ;

Nielsen, HU ;

Kaltoft, MS ;

Konradsen, HB .

JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (09) :4442-4444

[14] Failure of rifampin to eradicate group B streptococcal colonization in infants [J].

Fernandez, M ;

Rench, MA ;

Albanyan, EA ;

Edwards, MS ;

Baker, CJ .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2001, 20 (04) :371-376

[15] RECURRENT GROUP-B STREPTOCOCCAL INFECTIONS IN INFANTS - CLINICAL AND MICROBIOLOGIC ASPECTS [J].

GREEN, PA ;

SINGH, KV ;

MURRAY, BE ;

BAKER, CJ .

JOURNAL OF PEDIATRICS, 1994, 125 (06) :931-938

[16]

HANDWERGER S, 1985, REV INFECT DIS, V7, P368

[17] DELAYED RECURRENCE OF GROUP-B STREPTOCOCCAL INFECTION IN A NEWBORN-INFANT - A CASE-REPORT [J].

HAQUE, KN ;

BASHIR, O ;

KAMBAL, AMM .

ANNALS OF TROPICAL PAEDIATRICS, 1986, 6 (03) :219-220

[18] RELAPSING INVASIVE GROUP-B STREPTOCOCCAL INFECTION IN ADULTS [J].

HARRISON, LH ;

ALI, A ;

DWYER, DM ;

LIBONATI, JP ;

REEVES, MW ;

ELLIOTT, JA ;

BILLMANN, L ;

LASHKERWALA, T ;

JOHNSON, JA .

ANNALS OF INTERNAL MEDICINE, 1995, 123 (06) :421-427

[19] Serotype distribution of invasive group B streptococcal isolates in Maryland: Implications for vaccine formulation [J].

Harrison, LH ;

Elliott, JA ;

Dwyer, DM ;

Libonati, JP ;

Ferrieri, P ;

Billmann, L ;

Schuchat, A .

JOURNAL OF INFECTIOUS DISEASES, 1998, 177 (04) :998-1002

[20] Group B streptococcal disease in UK and Irish infants younger than 90 days [J].

Heath, PGT ;

Balfour, G ;

Weisner, AM ;

Efstratiou, A ;

Lamagni, TL ;

Tighe, H ;

O'Connell, LAF ;

Cafferkey, M ;

Verlander, NQ ;

Nicoll, A ;

McCartney, AC .

LANCET, 2004, 363 (9405) :292-294

← 1 2 3 4 5 →