Immunology of human endometrium

被引：48

作者：

Kämmerer, U

von Wolff, M

Markert, UR

机构：

[1] Univ Jena, Abt Geburtshilfe, D-07740 Jena, Germany

[2] Univ Frauenklin Heidelberg, Gynakol Endokrinol & Fertilitatsstorungen, Heidelberg, Germany

[3] Univ Wurzburg, Frauneklin, Wurzburg, Germany

来源：

IMMUNOBIOLOGY | 2004年 / 209卷 / 07期

关键词：

pregnancy; decidua; dendritic cells; T cells; NK cells; signal transduction;

D O I：

10.1016/j.imbio.2004.04.009

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In pregnancy, the endometrium represents the hosting surface for invading semi-allogeneic cells. A very fine tuning of cellular interactions is indispensible for the successful symbiosis of mother and fetus. Such interactions include a variety of immune cells, which are present in extremely high concentrations, and trophoblast cells. A wide spectrum of soluble and surface molecules is involved in homing, activation and switching of lymphocyte functions, but also in regulation of embryo implantation and control of trophoblast invasion. This mini-review provides a brief overview of immunological features of the endometrium. (C) 2004 Elsevier GmbH. All rights reserved.

引用

页码：569 / 574

页数：6

共 43 条

[1] Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis [J].