Complexation of small neutral organic molecules by water soluble calix[4]arenes

被引：110

作者：

Arena, G

Contino, A

Gulino, FG

Magri, A

Sciotto, D

Ungaro, R

机构：

[1] Univ Catania, Dipartimento Sci Chim, I-95125 Catania, Italy

[2] Univ Parma, Dipartimento Chim Organ & Ind, I-43100 Parma, Italy

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 48期

关键词：

calixarenes; molecular recognition; NMR;

D O I：

10.1016/S0040-4039(00)01687-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The inclusion of small neutral organic guests (alcohols, ketones and nitriles) by water-soluble calix[4]arene receptors was studied by H-1 NMR spectroscopy at neutral pH. The guests are included into the host hydrophobic cavity by their apolar aliphatic residues. The binding constants, determined by H-1 NMR titrations, confirm the importance of charge assistance in the apolar binding of guests inside calixarene cavities and highlight the role played by the conformational properties of the receptors in the recognition process. (C) 2000 Elsevier Science Ltd. All rights reserved.

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页码：9327 / 9330

页数：4

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