Rate of deprotonation of a simple ketone by lithium diisopropylamide

被引：19

作者：

Majewski, M ^{[1
]}

Nowak, P ^{[1
]}

机构：

[1] Univ Saskatchewan, Dept Chem, Saskatoon, SK S7N 5C9, Canada

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 13期

关键词：

D O I：

10.1016/S0040-4039(98)00015-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Rate studies on deprotonation of a simple ketone (R-2,2,6-trimethylcyclohexanone) with lithium diisopropylamide are described. The data are consistent with the reaction being first order in ketone and half order in the base, corresponding to the rate equation: v = k[ketone][LDA](1/2). (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：1661 / 1664

页数：4

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