Iron-catalysed sp3-sp3 cross-coupling reactions of unactivated alkyl halides with alkyl Grignard reagents

被引：115

作者：

Dongol, Krishna G. ^{[1
]}

Koh, Huishi ^{[1
]}

Sau, Manisankar ^{[1
]}

Chai, Christina L. L. ^{[1
]}

机构：

[1] Inst Chem & Engn Sci, Singapore 627833, Singapore

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2007年 / 349卷 / 07期

关键词：

alkyl halides; cross-coupling; Grignard reactions; iron;

D O I：

10.1002/adsc.200600383

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Iron-catalysed sp(3)-sp(3) Kumada coupling with primary and secondary alkyl halides (RX) and alkyl Grignard reagents has been achieved in low to good yields depending on the nature of the R group.

引用

页码：1015 / 1018

页数：4

共 19 条

[11] Catalysts for cross-coupling reactions with non-activated alkyl halides
Frisch, AC
Beller, M
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (05) : 674 - 688
[12] Fürstner A, 2002, ANGEW CHEM INT EDIT, V41, P609
[13] Advances in iron catalyzed cross coupling reactions
Fürstner, A
Martin, R
[J]. CHEMISTRY LETTERS, 2005, 34 (05) : 624 - 629
[14] Iron-catalyzed cross-coupling reactions
Fürstner, A
Leitner, A
Méndez, M
Krause, H
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (46) : 13856 - 13863
[15] Convenient titration method for organometallic zinc, magnesium, and lanthanide reagents
Krasovskiy, A
Knochel, P
[J]. SYNTHESIS-STUTTGART, 2006, (05): : 890 - 891
[16] Iron-catalyzed Grignard cross-coupling with alkyl halides possessing β-hydrogens
Nagano, T
Hayashi, T
[J]. ORGANIC LETTERS, 2004, 6 (08) : 1297 - 1299
[17] Iron-catalyzed cross-coupling of primary and secondary alkyl halides with aryl Grignard reagents
Nakamura, M
Matsuo, K
Ito, S
Nakamura, E
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (12) : 3686 - 3687
[18] IRON CATALYSIS IN REACTION OF GRIGNARD REAGENTS WITH ALKYL HALIDES
TAMURA, M
KOCHI, J
[J]. JOURNAL OF ORGANOMETALLIC CHEMISTRY, 1971, 31 (03) : 289 - &
[19] VINYLATION OF GRIGNARD REAGENTS - CATALYSIS BY IRON
TAMURA, M
KOCHI, J
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1971, 93 (06) : 1487 - &

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