Wide field-of-view lens-free fluorescent imaging on a chip

被引：80

作者：

Coskun, Ahmet F. ^{[1
]}

Su, Ting-Wei ^{[1
]}

Ozcan, Aydogan ^{[1
,2
]}

机构：

[1] Univ Calif Los Angeles, Dept Elect Engn, Los Angeles, CA 90095 USA

[2] Univ Calif Los Angeles, CNSI, Los Angeles, CA 90095 USA

来源：

LAB ON A CHIP | 2010年 / 10卷 / 07期

基金：

美国国家科学基金会;

关键词：

MICROSCOPY; GUIDE;

D O I：

10.1039/b926561a

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We demonstrate an on-chip fluorescent detection platform that can simultaneously image fluorescent micro-objects or labeled cells over an ultra-large field-of-view of 2.5 cm x 3.5 cm without the use of any lenses, thin-film filters and mechanical scanners. Such a wide field-of-view lensless fluorescent imaging modality, despite its limited resolution, might be very important for high-throughput screening applications as well as for detection and counting of rare cells within large-area microfluidic devices.

引用

页码：824 / 827

页数：4

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