GeneBins: a database for classifying gene expression data, with application to plant genome arrays

被引:38
作者
Goffard, Nicolas
Weiller, Georg
机构
[1] Australian Natl Univ, ARC Ctr Excellence Integrat Legume Res, Canberra, ACT 2601, Australia
[2] Australian Natl Univ, Bioinformat Lab, Genom Interact Grp, Res Sch Biol Sci, Canberra, ACT 2601, Australia
关键词
D O I
10.1186/1471-2105-8-87
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Background: To interpret microarray experiments, several ontological analysis tools have been developed. However, current tools are limited to specific organisms. Results: We developed a bioinformatics system to assign the probe set sequences of any organism to a hierarchical functional classification modelled on KEGG ontology. The GeneBins database currently supports the functional classification of expression data from four Affymetrix arrays; Arabidopsis thaliana, Oryza sativa, Glycine max and Medicago truncatula. An online analysis tool to identify relevant functions is also provided. Conclusion: GeneBins provides resources to interpret gene expression results from microarray experiments. It is available at http://bioinfoserver.rsbs.anu.edu.au/utils/GeneBins/.
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页数:5
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