An array of possibilities in cancer research using cytokine antibody arrays

被引：27

作者：

Huang, Ruo-Pan ^{[1
]}

机构：

[1] Emory Univ, Sch Med, Dept Gynecol & Obstet, Atlanta, GA 30322 USA

来源：

EXPERT REVIEW OF PROTEOMICS | 2007年 / 4卷 / 02期

关键词：

antibody array; biomarker; cancer; cytokine; drug discovery; expression profile; proteomics;

D O I：

10.1586/14789450.4.2.299

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Protein arrays have shown potential applications in cancer research. After several decades of research, it has become evident that many cytokines are central to the development of cancer and its treatment. Cytokine antibody arrays that have been designed to simultaneously detect multiple cytokines are not only available, but show a diversity of applications in the study of many diseases in addition to cancer. This review will focus on the implementation of cytokine antibody arrays in many aspects of cancer research, such as biomarker discovery, molecular mechanisms of cancer development, preclinical studies and the effects of cancer compounds.

引用

页码：299 / 308

页数：10

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