Light-induced reversible formation of polymeric micelles

被引:320
作者
Lee, Hyung-il [1 ]
Wu, Wei [1 ]
Oh, Jung Kwon [1 ]
Mueller, Laura [1 ]
Sherwood, Gizelle [1 ]
Peteanu, Linda [1 ]
Kowalewski, Tomasz [1 ]
Matyjaszewski, Krzysztof [1 ]
机构
[1] Carnegie Mellon Univ, Dept Chem, Ctr Macromol Engn, Pittsburgh, PA 15213 USA
关键词
block copolymers; isomerization; micelles; polymerization;
D O I
10.1002/anie.200604278
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Figure Presented) Reversible disruption and regeneration of block-copolymer micelles has been achieved by UV and visible-light irradiation and studied by atomic force microscopy (see picture). A hydrophobic dye encapsulated in the original polymeric micelles was released after UV irradiation. Remarkably, some of the released hydrophobic dye was re-encapsulated on regeneration of the micelles by irradiation with visible light. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:2453 / 2457
页数:5
相关论文
共 24 条
[1]   Atom transfer radical copolymerization of styrene and n-butyl acrylate [J].
Arehart, SV ;
Matyjaszewski, K .
MACROMOLECULES, 1999, 32 (07) :2221-2231
[2]   Spiropyrans and spirooxazines for memories and switches [J].
Berkovic, G ;
Krongauz, V ;
Weiss, V .
CHEMICAL REVIEWS, 2000, 100 (05) :1741-1753
[3]   BIODEGRADABLE LONG-CIRCULATING POLYMERIC NANOSPHERES [J].
GREF, R ;
MINAMITAKE, Y ;
PERACCHIA, MT ;
TRUBETSKOY, V ;
TORCHILIN, V ;
LANGER, R .
SCIENCE, 1994, 263 (5153) :1600-1603
[4]   Synthesis and spectral investigations of a new dyad with spiropyran and fluorescein units: Toward information processing at the single molecular level [J].
Guo, XF ;
Zhang, XF ;
Zhang, DQ ;
Zhou, YC ;
Zhu, DB .
JOURNAL OF ORGANIC CHEMISTRY, 2003, 68 (14) :5681-5687
[5]   Supramolecular drug-delivery systems based on polymeric core-shell architectures [J].
Haag, R .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2004, 43 (03) :278-282
[6]   Enzyme modification by polymers with solubilities that change in response to photoirradiation in organic media [J].
Ito, Y ;
Sugimura, N ;
Kwon, OH ;
Imanishi, Y .
NATURE BIOTECHNOLOGY, 1999, 17 (01) :73-75
[7]   Self-assembled aggregates of rod-coil block copolymers and their solubilization and encapsulation of fullerenes [J].
Jenekhe, SA ;
Chen, XL .
SCIENCE, 1998, 279 (5358) :1903-1907
[8]   A light-actuated nanovalve derived from a channel protein [J].
Koçer, A ;
Walko, M ;
Meijberg, W ;
Feringa, BL .
SCIENCE, 2005, 309 (5735) :755-758
[9]   Phototunable temperature-responsive molecular brushes prepared by ATRP [J].
Lee, Hyung-il ;
Pietrasik, Joanna ;
Matyjaszewski, Krzysztof .
MACROMOLECULES, 2006, 39 (11) :3914-3920
[10]   Inverse miniemulsion ATRP: A new method for synthesis and functionalization of well-defined water-soluble/cross-linked polymeric particles [J].
Oh, JK ;
Tang, CB ;
Gao, HF ;
Tsarevsky, NV ;
Matyjaszewski, K .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (16) :5578-5584