Kindling induces a transient suppression of afterhyperpolarization in rat subicular neurons

被引：25

作者：

Behr, J ^{[1
]}

Gloveli, T ^{[1
]}

Heinemann, U ^{[1
]}

机构：

[1] Humboldt Univ, Univ Hosp Charite, Inst Physiol, Dept Neurophysiol, D-10117 Berlin, Germany

来源：

BRAIN RESEARCH | 2000年 / 867卷 / 1-2期

关键词：

intracellular recording; bursting cell; regular firing cell; accommodation; afterhyperpolarization;

D O I：

10.1016/S0006-8993(00)02324-6

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

To determine whether chronic epilepsy induces persistent cellular changes in subicular neurons intracellular recordings were used to compare membrane properties of control and kindled rats. In both, control and kindled preparations the subiculum contained regular firing cells and an extensive sub-population of bursting cells expressing amplifying membrane characteristics. Subicular cells showed a transient depression of the fast and slow AHP in the course of kindling that may contribute to the induction but not permanence of the kindled state. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：259 / 264

页数：6

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