Maturation of cellular Fe-S proteins: an essential function of mitochondria

被引：302

作者：

Lill, R

Kispal, G

机构：

[1] Univ Marburg, Inst Zytobiol & Zytopathol, D-35033 Marburg, Germany

[2] Univ Pecs, Sch Med, Inst Biochem, H-7624 Pecs, Hungary

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 2000年 / 25卷 / 08期

关键词：

D O I：

10.1016/S0968-0004(00)01589-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Iron-sulfur (Fe-S) cluster-containing proteins perform important tasks in catalysis, electron transfer and regulation of gene expression. In eukaryotes! mitochondria are the primary site of cluster formation of most Fe-S proteins. Assembly of the Fe-S clusters is mediated by the iron-sulphate cluster assembly (ISC) machinery consisting of some ten proteins.

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页码：352 / 356

页数：5

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