The synthesis of amines by the homogeneous hydrogenation of secondary and primary amides

被引：185

作者：

Nunez, Angel A.

Eastham, Graham R.

Cole-Hamilton, David J. ^{[1
]}

机构：

[1] Univ St Andrews, Sch Chem, St Andrews KY16 9ST, Fife, Scotland

[2] Ctr Technol, Lucite Int, Middlesbrough TS6 8JE, Cleveland, England

来源：

CHEMICAL COMMUNICATIONS | 2007年 / 30期

关键词：

D O I：

10.1039/b706635j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Amides can be hydrogenated to amines using a catalyst prepared in situ from [Ru(acac)(3)] and 1,1,1- tris(diphenylphosphinomethyl) ethane; water is required to stabilize the catalyst and primary amines can only be formed (selectivity up to 85%) if ammonia is also present.

引用

页码：3154 / 3156

页数：3

共 16 条

[1]

ADKINS H, 1954, ORG REACTIONS, V8, P1

[2] TRIPODAL POLYPHOSPHINE LIGANDS CONTROL SELECTIVITY OF ORGANOMETALLIC REACTIONS [J].