Aromatic nucleophilic substitutions under microwave irradiation

被引：22

作者：

Salmoria, GV ^{[1
]}

Dall'Oglio, E ^{[1
]}

Zucco, C ^{[1
]}

机构：

[1] Univ Fed Santa Catarina, Dept Quim, BR-88040900 Florianopolis, SC, Brazil

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 17期

关键词：

D O I：

10.1016/S0040-4039(98)00308-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In order to study the effect of microwave irradiation over aromatic nucleophilic substitutions at atmospheric pressure and in a homogeneous medium experiments with disubstituted-benzenes and the nucleophiles piperidine and potassium t-butoxide, in refluxing DMSO or DMF, were carried out. The aromatic nucleophilic substitutions under microwave irradiation were 2.7 to 12 times faster than under coventional reflux. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：2471 / 2474

页数：4

共 19 条

[1] APPLICATION OF MICROWAVE-ENERGY TO ORGANIC-SYNTHESIS - IMPROVED TECHNOLOGY
ABRAMOVITCH, RA
ABRAMOVITCH, DA
IYANAR, K
TAMARESELVY, K
[J]. TETRAHEDRON LETTERS, 1991, 32 (39) : 5251 - 5254
[2] NUCLEOPHILIC DISPLACEMENTS OF ACTIVATED FLUORINE IN AROMATIC COMPOUNDS
BADER, H
HANSEN, AR
MCCARTY, FJ
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1966, 31 (07) : 2319 - &
[3] A NEW REACTION VESSEL FOR ACCELERATED SYNTHESES USING MICROWAVE DIELECTRIC SUPER-HEATING EFFECTS
BAGHURST, DR
MINGOS, DMP
[J]. JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 1992, (07): : 1151 - 1155
[4] BALAS L, 1990, B SOC CHIM FR, P401
[5] ORGANIC-SYNTHESIS IN MICROWAVE FIELD - 1ST EXAMPLE OF SPECIFIC ACTIVATION UNDER HOMOGENEOUS CONDITIONS
BERLAN, J
GIBOREAU, P
LEFEUVRE, S
MARCHAND, C
[J]. TETRAHEDRON LETTERS, 1991, 32 (21) : 2363 - 2366
[6] Bottcher C. J. F., 1978, THEORY ELECT POLARIZ, V1
[7] Bottcher C. J. F., 1978, THEORY ELECT POLARIZ, VII
[8] NUCLEOPHILIC SUBSTITUTION IN THE BENZENE RING .1. RATES OF REACTIONS OF PARA-SUBSTITUTED BROMOBENZENES WITH PIPERIDINE
BUNNETT, JF
LEVITT, A
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1948, 70 (08) : 2778 - 2779
[9] DRY HYDROLYSIS OF NITRITES EFFECTED BY MICROWAVE-HEATING
CHEMAT, F
POUX, M
BERLAN, J
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1994, (12): : 2597 - 2602
[10] Dean J.A., 1985, LANGES HDB CHEM, V13

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