A mild and efficient one-step synthesis of quinolines

被引:157
作者
De, SK [1 ]
Gibbs, RA [1 ]
机构
[1] Purdue Univ, Ctr Canc, Dept Med Chem & Mol Pharmacol, W Lafayette, IN 47906 USA
关键词
D O I
10.1016/j.tetlet.2005.01.075
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
2-Artimoaryl ketones undergo condensation with alpha-methylene ketones in the presence of a catalytic amount of Y(OTf)(3) at room temperature under mild conditions to afford the corresponding polysubstituted quinolines in excellent yields. (C) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1647 / 1649
页数:3
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