A matter of life or death

被引:10
作者
Ranganathan, R [1 ]
机构
[1] Univ Texas, SW Med Ctr, Dept Pharmacol, Howard Hughes Med Inst, Dallas, TX 75390 USA
关键词
D O I
10.1126/science.1082509
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
[No abstract available]
引用
收藏
页码:1677 / 1679
页数:3
相关论文
共 14 条
[1]   Modulating sphingolipid biosynthetic pathway rescues photoreceptor degeneration [J].
Acharya, U ;
Patel, S ;
Koundakjian, E ;
Nagashima, K ;
Han, X ;
Acharya, JK .
SCIENCE, 2003, 299 (5613) :1740-1743
[2]   Mechanisms of photoreceptor death in retinal degenerations: From the cell biology of the 1990s to the ophthalmology of the 21st century? [J].
Adler, R .
ARCHIVES OF OPHTHALMOLOGY, 1996, 114 (01) :79-83
[3]   The formation of stable rhodopsin-arrestin complexes induces apoptosis and photoreceptor cell degeneration [J].
Alloway, PG ;
Howard, L ;
Dolph, PJ .
NEURON, 2000, 28 (01) :129-138
[4]   Sphingomyelin hydrolysis during apoptosis [J].
Andrieu-Abadie, N ;
Levade, T .
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2002, 1585 (2-3) :126-134
[5]   Regulation of SREBP processing and membrane lipid production by phospholipids in Drosophila [J].
Dobrosotskaya, IY ;
Seegmiller, AC ;
Brown, MS ;
Goldstein, JL ;
Rawson, RB .
SCIENCE, 2002, 296 (5569) :879-883
[6]   Sphingoid base signaling via Pkh kinases is required for endocytosis in yeast [J].
Friant, S ;
Lombardi, R ;
Schmelzle, T ;
Hall, MN ;
Riezman, H .
EMBO JOURNAL, 2001, 20 (23) :6783-6792
[7]   Enhanced phagocytosis through inhibition of de novo ceramide synthesis [J].
Hinkovska-Galcheva, V ;
Boxer, L ;
Mansfield, PJ ;
Schreiber, AD ;
Shayman, JA .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (02) :974-982
[8]   Single amino acid change in the fifth transmembrane segment of the TRP Ca2+ channel causes massive degeneration of photoreceptors [J].
Hong, YS ;
Park, SY ;
Geng, CX ;
Baek, KH ;
Bowman, JD ;
Yoon, JS ;
Pak, WL .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (37) :33884-33889
[9]   A molecular pathway for light-dependent photoreceptor apoptosis in Drosophila [J].
Kiselev, A ;
Socolich, M ;
Vinós, J ;
Hardy, RW ;
Zuker, CS ;
Ranganathan, R .
NEURON, 2000, 28 (01) :139-152
[10]   The mitochondrial death/life regulator in apoptosis and necrosis [J].
Kroemer, G ;
Dallaporta, B ;
Resche-Rigon, M .
ANNUAL REVIEW OF PHYSIOLOGY, 1998, 60 :619-642