Synthesis of Alkyl Alkynyl Ketones by Pd/Light-Induced Three-Component Coupling Reactions of Iodoalkanes, CO, and 1-Alkynes

被引：109

作者：

Fusano, Akira ^{[1
]}

Fukuyama, Takahide ^{[1
]}

Nishitani, Satoshi ^{[1
]}

Inouye, Takaya ^{[1
]}

Ryu, Ilhyong ^{[1
]}

机构：

[1] Osaka Prefecture Univ, Grad Sch Sci, Dept Chem, Osaka 5998531, Japan

来源：

ORGANIC LETTERS | 2010年 / 12卷 / 10期

关键词：

ATOM-TRANSFER CARBONYLATION; PD-CATALYZED CARBONYLATION; VALENT METAL-COMPLEXES; CARBON-MONOXIDE; ACETYLENIC KETONES; RADICAL REACTIONS; ARYL IODIDES; TERMINAL ACETYLENES; OXIDATIVE ADDITION; ACYL CHLORIDES;

D O I：

10.1021/ol1007668

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Under photoirradiation conditions using xenon light, In the presence of a catalytic amount of PdCl2(PPh3)(2) with triethylamine as a base, a three-component coupling reaction of iodoalkanes, carbon monoxide, and terminal alkynes proceeded to give alkyl alkynyl ketones in good yields.

引用

页码：2410 / 2413

页数：4

共 52 条

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