Association of human papillomavirus type 6 with a verruciform xanthoma

被引：37

作者：

Khaskhely, NM

Uezato, H

Kamiyama, T

Maruno, M

Kariya, K

Oshiro, M

Nonaka, S

机构：

[1] Univ Ryukyus, Fac Med, Dept Dermatol, Nishihara, Okinawa 9030215, Japan

[2] Univ Ryukyus, Fac Med, Dept Biochem 2, Nishihara, Okinawa 9030215, Japan

来源：

AMERICAN JOURNAL OF DERMATOPATHOLOGY | 2000年 / 22卷 / 05期

关键词：

human papillomavirus; polymerase chain reaction; verruciform xanthoma;

D O I：

10.1097/00000372-200010000-00012

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

We report a case of verruciform xanthoma (VX) associated with human papillomavirus (HPV) in a 67-year-old male. The patient had a pale-reddish, granular and verrucous tumor on the right side of his scrotum For four years. Histopathologic examination showed typical features of VX. I-IPV was detected by immunohistochemistry, electron microscopy, and PCR examinations. Ultrastructural examination revealed virus-like particles of 40-50 nm in the nucleus of the upper epidermal keratinocytes. HPV type 6a. DNA was detected in lesional tissue by polymerase chain reaction and sequence analysis. To the best of our knowledge, this is the first case report of VX associated with HPV.

引用

页码：447 / 452

页数：6

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