Transcriptional analysis of genes encoding Shiga toxin 2 and its variants in Escherichia coli

被引：49

作者：

Zhang, W ^{[1
]}

Bielaszewska, M ^{[1
]}

Friedrich, AW ^{[1
]}

Kuczius, T ^{[1
]}

Karch, H ^{[1
]}

机构：

[1] Univ Klinikum Munster, Inst Hyg, D-48149 Munster, Germany

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2005年 / 71卷 / 01期

关键词：

D O I：

10.1128/AEM.71.1.558-561.2005

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Six of 37 non-O157 Escherichia coli strains possessing Shiga toxin (Stx) 2 gene variant stx(2d) or stx(2e) secreted no detectable Stx. These isolates produced significantly less stx mRNA than Stx2d, Stx2e, Stx2c, or Stx2 secretors did. Standard screening procedures miss a significant subset of E. coli harboring stx(2) variants.

引用

页码：558 / 561

页数：4

共 22 条

[1] Escherichia coli O157:H7 infections:: Discordance between filterable fecal Shiga toxin and disease outcome
Cornick, NA
Jelacic, S
Ciol, MA
Tarr, PI
[J]. JOURNAL OF INFECTIOUS DISEASES, 2002, 186 (01) : 57 - 63
[2] CONSTRUCTION OF RECOMBINANT SHIGA-LIKE TOXIN-IIV (SLT-IIV) AND ITS USE IN MONITORING THE SLT-IIV ANTIBODY STATUS OF PIGS
FRANKE, S
GUNZER, F
WIELER, LH
BALJER, G
KARCH, H
[J]. VETERINARY MICROBIOLOGY, 1995, 43 (01) : 41 - 52
[3] Escherichia coli harboring shiga toxin 2 gene variants:: frequency and association with clinical symptoms
Friedrich, AW
Bielaszewska, M
Zhang, WL
Pulz, M
Kuczius, T
Ammon, A
Karch, H
[J]. JOURNAL OF INFECTIOUS DISEASES, 2002, 185 (01) : 74 - 84
[4] EVIDENCE THAT GLUTAMIC ACID-167 IS AN ACTIVE-SITE RESIDUE OF SHIGA-LIKE TOXIN-I
HOVDE, CJ
CALDERWOOD, SB
MEKALANOS, JJ
COLLIER, RJ
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (08) : 2568 - 2572
[5] Shiga toxin-producing Escherichia coli in Montana:: Bacterial genotypes and clinical profiles
Jelacic, JK
Damrow, T
Chen, GS
Jelacic, S
Bielaszewska, M
Ciol, M
Carvalho, HM
Melton-Celsa, AR
O'Brien, AD
Tarr, PI
[J]. JOURNAL OF INFECTIOUS DISEASES, 2003, 188 (05) : 719 - 729
[6] THE ASSOCIATION BETWEEN IDIOPATHIC HEMOLYTIC UREMIC SYNDROME AND INFECTION BY VEROTOXIN-PRODUCING ESCHERICHIA-COLI
KARMALI, MA
PETRIC, M
LIM, C
FLEMING, PC
ARBUS, GS
LIOR, H
[J]. JOURNAL OF INFECTIOUS DISEASES, 1985, 151 (05) : 775 - 782
[7] Identification of an insertion sequence, IS1203 variant, in a Shiga toxin 2 gene of Escherichia coli O157:H7
Kusumoto, M
Nishiya, Y
Kawamura, Y
Shinagawa, K
[J]. JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 1999, 87 (01) : 93 - 96
[8] A newly discovered verotoxin variant, VT2g, produced by bovine verocytotoxigenic Escherichia coli
Leung, PHM
Peiris, JSM
Ng, WWS
Robins-Browne, RM
Bettelheim, KA
Yam, WC
[J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2003, 69 (12) : 7549 - 7553
[9] Activation of Shiga-like toxins by mouse and human intestinal mucus correlates with virulence of enterohemorrhagic Escherichia coli O91:H21 isolates in orally infected, streptomycin-treated mice
MeltonCelsa, AR
Darnell, SC
OBrien, AD
[J]. INFECTION AND IMMUNITY, 1996, 64 (05) : 1569 - 1576
[10] Characterization of a Shiga toxin 2e-converting bacteriophage from an Escherichia coli strain of human origin
Muniesa, M
Recktenwald, J
Bielaszewska, M
Karch, H
Schmidt, H
[J]. INFECTION AND IMMUNITY, 2000, 68 (09) : 4850 - 4855

← 1 2 3 →