Crystal engineering of the composition of pharmaceutical phases

被引：393

作者：

Walsh, RDB

Bradner, MW

Fleischman, S

Morales, LA

Moulton, B

Rodríguez-Hornedo, N

Zaworotko, MJ

机构：

[1] Univ S Florida, Dept Chem, Tampa, FL 33620 USA

[2] Univ Michigan, Coll Pharm, Dept Pharmaceut Sci, Ann Arbor, MI 48109 USA

来源：

CHEMICAL COMMUNICATIONS | 2003年 / 02期

关键词：

D O I：

10.1039/b208574g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The carboxylic acid-pyridine supramolecular heterosynthon can be exploited to predictably generate binary crystalline phases involving rac-ibuprofen, rac-flurbiprofen or aspirin.

引用

页码：186 / 187

页数：2

共 27 条

[21] Crystallization processes in pharmaceutical technology and drug delivery design [J].

Shekunov, BY ;

York, P .

JOURNAL OF CRYSTAL GROWTH, 2000, 211 (1-4) :122-136

[22]

Sheldrick G.M., 1996, SADABS VERSION 2008

[23]

SHELDRICK GM, 2000, SHELXTL RELEASE 6 10

[24]

Steiner T, 2002, ANGEW CHEM INT EDIT, V41, P48, DOI 10.1002/1521-3773(20020104)41:1<48::AID-ANIE48>3.0.CO

[25]

2-U

[26] Recurrence of carboxylic acid-pyridine supramolecular synthon in the crystal structures of some pyrazinecarboxylic acids [J].

Vishweshwar, P ;

Nangia, A ;

Lynch, VM .

JOURNAL OF ORGANIC CHEMISTRY, 2002, 67 (02) :556-565

[27] Crystal engineering using anilic acids and dipyridyl compounds through a new supramolecular synthon [J].

Zaman, MB ;

Tomura, M ;

Yamashita, Y .

JOURNAL OF ORGANIC CHEMISTRY, 2001, 66 (18) :5987-5995

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