Ethenzamide-gentisic acid-acetic acid (2/1/1)

In the title co-crystal solvate, 2-ethoxybenzamide-2,5-dihydroxybenzoic acid-ethanoic acid (2/1/1), 2C(9)H(11)NO(2)center dot C7H6O4 center dot C2H4O2, two nonsteroidal anti-inflammatory drugs, ethenzamide (systematic name: 2-ethoxybenzamide) and gentisic acid (systematic name: 2,5-dihydroxybenzoic acid), together with acetic acid (systematic name: ethanoic acid) form a four-component molecular assembly held together by N-H center dot center dot center dot O and O-H center dot center dot center dot O hydrogen bonds. This assembly features two symmetry-independent molecules of ethenzamide, forming supramolecular acid-amide heterosynthons with gentisic acid and acetic acid. These heterosynthons involve quite strong O-H center dot center dot center dot O [O center dot center dot center dot O = 2.5446 (15) and 2.5327 (15) angstrom] and less strong N-H center dot center dot center dot O [N center dot center dot center dot O = 2.9550 (17) and 2.9542 (17) angstrom] hydrogen bonds. The overall crystal packing features several C-H center dot center dot center dot O and pi-pi stacking interactions [centroid-centroid distance = 3.7792 (11) angstrom].