Models for the molybdenum hydroxylases

被引：32

作者：

Young, CG ^{[1
]}

机构：

[1] Univ Melbourne, Sch Chem, Parkville, Vic 3052, Australia

来源：

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY | 1997年 / 2卷 / 06期

关键词：

molybdoenzyme; hydroxylases; xanthine oxidase; aldehyde oxidoreductase; molybdenum-sulfur complexes;

D O I：

10.1007/s007750050200

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This commentary reviews structural, spectroscopic, and chemical models for the molybdenum hydroxylases. It briefly describes the current state of modeling and identifies areas where model chemistry may play a future role in understanding these enzymes.

引用

页码：810 / 816

页数：7

共 66 条

[11] The structure and mode of action of the cofactor of the oxomolybdoenzymes [J].

Collison, D ;

Garner, CD ;

Joule, JA .

CHEMICAL SOCIETY REVIEWS, 1996, 25 (01) :25-+

[12] REACTIVITY OF THE MO(O)(S) FUNCTIONAL-GROUP IN THE [(L)MO(O)(MU-S)2MO(O)(S)]N- DIMERIC THIOMOLYBDATE COMPLEXES (L=C5H5-, N=1-,S4(2-), N=2) AND IMPLICATIONS REGARDING THE FUNCTION OF XANTHINE-OXIDASE - SYNTHESIS AND STRUCTURAL CHARACTERIZATION OF [(DMF)3MO(O)(MU-S)2MO(O)(S2)], [PH4P][(C5H5)MO(O)(MU-S)2MO(O)(S2)], [PH4P]2[(S4)MO(O)(MU-S)2MO(O)(S)], AND (ET4N)4([(S4)MO(O)(MU-S)2MO(O)(S)]2) [J].

COUCOUVANIS, D ;

TOUPADAKIS, A ;

LANE, JD ;

KOO, SM ;

KIM, CG ;

HADJIKYRIACOU, A .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (14) :5271-5282

[13] STUDIES OF THE REACTIVITY OF BINARY THIOMOLYBDATES AND TERTIARY OXOTHIOMOLYBDATES TOWARD ELECTROPHILES - REACTIONS WITH DICARBOMETHOXYACETYLENE AND THE SYNTHESIS AND STRUCTURES OF THE [ET4N]2[MOO(L)2], ANTI-[ET4N]2[MO2O2S2(L)2], SYN-[PH4P]2[MO2O2S2(L)2].2DMF, [PH4P]2[MO(L)3].DMF.C6H6, AND [PH4P]2[MO2S2(L)4].2CH2CL2 COMPLEXES (L = 1,2-DICARBOMETHOXY-1,2-ETHYLENEDITHIOLATE) [J].

COUCOUVANIS, D ;

HADJIKYRIACOU, A ;

TOUPADAKIS, A ;

KOO, SM ;

ILEPERUMA, O ;

DRAGANJAC, M ;

SALIFOGLOU, A .

INORGANIC CHEMISTRY, 1991, 30 (04) :754-767

[14] ORIGIN OF CYANOLYSABLE SULFUR IN MOLYBDENUM IRON-SULFUR FLAVIN HYDROXYLASES [J].

COUGHLAN, MP .

FEBS LETTERS, 1977, 81 (01) :1-7

[15] CONVERSION OF [MOS4]2- TO [MO2S2(MU-S)2(S2)2]2- BY ORGANIC DISULFIDES - THE MECHANISM OF AN INDUCED REDOX REACTION [J].

COYLE, CL ;

HARMER, MA ;

GEORGE, GN ;

DAAGE, M ;

STIEFEL, EI .

INORGANIC CHEMISTRY, 1990, 29 (01) :14-19

[16] MOLYBDENUM SITES OF SULFITE OXIDASE AND XANTHINE DEHYDROGENASE - A COMPARISON BY EXAFS [J].

CRAMER, SP ;

WAHL, R ;

RAJAGOPALAN, KV .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1981, 103 (26) :7721-7727

[17] ARSENITE-INHIBITED XANTHINE-OXIDASE - DETERMINATION OF THE MO-S-AS GEOMETRY BY EXAFS [J].

CRAMER, SP ;

HILLE, R .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (26) :8164-8169

[18] FORMATION AND MOLECULAR-STRUCTURE OF DI-MU-OXO-DI[DI(BENZENETHIOLATO)-OXOMOLYBDATE(V)] DIANION [J].

DANCE, IG ;

WEDD, AG ;

BOYD, IW .

AUSTRALIAN JOURNAL OF CHEMISTRY, 1978, 31 (03) :519-526

[19] MODELING FOR THE ACTIVE-SITE OF SULFITE OXIDASE - SYNTHESIS, CHARACTERIZATION, AND REACTIVITY OF [(MOO2)-O-VI(MNT)(2)](2-) (MNT(2-)=1,2-DICYANOETHYLENEDITHIOLATE) [J].

DAS, SK ;

CHAUDHURY, PK ;

BISWAS, D ;

SARKAR, S .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (20) :9061-9070

[20] MOLYBDENUM(VI) AND MOLYBDENUM(V) COMPLEXES WITH N,N'-DIMETHYL-N,N'-BIS(2-MERCAPTOPHENYL)ETHYLENEDIAMINE - ELECTROCHEMICAL AND ELECTRON-PARAMAGNETIC RESONANCE MODELS FOR THE MOLYBDENUM(VI/V) CENTERS OF THE MOLYBDENUM HYDROXYLASES AND RELATED ENZYMES [J].

DOWERAH, D ;

SPENCE, JT ;

SINGH, R ;

WEDD, AG ;

WILSON, GL ;

FARCHIONE, F ;

ENEMARK, JH ;

KRISTOFZSKI, J ;

BRUCK, M .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (19) :5655-5665

← 1 2 3 4 5 6 7 →