Emergence and evolution of Vibrio cholerae O139

被引:123
作者
Faruque, SM
Sack, DA
Sack, RB
Colwell, RR
Takeda, Y
Nair, GB
机构
[1] Int Ctr Diarrhoeal Dis Res, Div Sci Lab, Dhaka 1212, Bangladesh
[2] Johns Hopkins Univ, Dept Int Hlth, Baltimore, MD 21205 USA
[3] Univ Maryland, Inst Biotechnol, Ctr Marine Biotechnol, Baltimore, MD 21202 USA
[4] Univ Maryland, Dept Cell Biol & Mol Genet, College Pk, MD 20742 USA
[5] Jissen Womens Univ, Fac Human Life Sci, Tokyo 1918510, Japan
关键词
D O I
10.1073/pnas.0337468100
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The emergence of Vibrio cholerae O139 Bengal during 1992-1993 was associated with large epidemics of cholera in India and Bangladesh and, initially, with a total displacement of the existing V. cholerae O1 strains. However, the O1 strains reemerged in 1994 and initiated a series of disappearance and reemergence of either of the two sero-groups that was associated with temporal genetic and phenotypic changes sustained by the strains. Since the initial emergence of the O139 vibrios, new variants of the pathogen derived from multiple progenitors have been isolated and characterized. The clinical and epidemiological characteristics of these strains have been studied. Rapid genetic reassortment in O139 strains appears to be a response to the changing epidemiology of V. cholerae O1 and also a strategy for persistence in competition with strains of the O1 serogroup. The emergence of V. cholerae O139 has provided a unique opportunity to witness genetic changes in V. cholerae that may be associated with displacement of an existing serogroup by a newly emerging one and, thus, provide new insights into the epidemiology of cholera. The genetic changes and natural selection involving both environmental and host factors are likely to influence profoundly the genetics, epidemiology, and evolution of toxigenic V. cholerae, not only in the Ganges Delta region of India and Bangladesh, but also in other areas of endemic and epidemic cholera.
引用
收藏
页码:1304 / 1309
页数:6
相关论文
共 59 条
  • [11] Centers for Disease Control and Prevention (CDC), 1993, MMWR-MORBID MORTAL W, V42, P501
  • [12] VIBRIO-CHOLERAE 0139 BENGAL IN BANGKOK
    CHONGSANGUAN, M
    CHAICUMPA, W
    MOOLASART, P
    KANDHASINGHA, P
    SHIMADA, T
    KURAZONO, H
    TAKEDA, Y
    [J]. LANCET, 1993, 342 (8868) : 430 - 431
  • [13] Cloning and sequence of a region encoding a surface polysaccharide of Vibrio cholerae O139 and characterization of the insertion site in the chromosome of Vibrio cholerae O1
    Comstock, LE
    Johnson, JA
    Michalski, JM
    Morris, JG
    Kaper, JB
    [J]. MOLECULAR MICROBIOLOGY, 1996, 19 (04) : 815 - 826
  • [14] Allelic diversity and population structure in Vibrio cholerae O139 Bengal based on nucleotide sequence analysis
    Farfán, M
    Miñana-Galbis, D
    Fusté, MC
    Lorén, JG
    [J]. JOURNAL OF BACTERIOLOGY, 2002, 184 (05) : 1304 - 1313
  • [15] Genetic relationships between clinical and environmental Vibrio cholerae isolates based on multilocus enzyme electrophoresis
    Farfán, M
    Miñana, D
    Fusté, MC
    Lorén, JG
    [J]. MICROBIOLOGY-SGM, 2000, 146 : 2613 - 2626
  • [16] Molecular characterization of a new ribotype of Vibrio cholerae O139 Bengal associated with an outbreak of cholera in Bangladesh
    Faruque, SM
    Siddique, AK
    Saha, MN
    Asadulghani
    Rahman, MM
    Zaman, K
    Albert, MJ
    Sack, DA
    Sack, RB
    [J]. JOURNAL OF CLINICAL MICROBIOLOGY, 1999, 37 (05) : 1313 - 1318
  • [17] Genomic diversity among Vibrio cholerae O139 strains isolated in Bangladesh and India between 1992 and 1998
    Faruque, SM
    Saha, MN
    Asadulghani
    Bag, PK
    Bhadra, RK
    Bhattacharya, SK
    Sack, RB
    Takeda, Y
    Nair, GB
    [J]. FEMS MICROBIOLOGY LETTERS, 2000, 184 (02) : 279 - 284
  • [18] Emergence of a new clone of toxigenic Vibrio cholerae 01 biotype El Tor displacing V-cholerae O139 Bengal in Bangladesh
    Faruque, SM
    Ahmed, KM
    Alim, ARMA
    Qadri, F
    Siddique, AK
    Albert, MJ
    [J]. JOURNAL OF CLINICAL MICROBIOLOGY, 1997, 35 (03) : 624 - 630
  • [19] Epidemiology, genetics, and ecology of toxigenic Vibrio cholerae
    Faruque, SM
    Albert, MJ
    Mekalanos, JJ
    [J]. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 1998, 62 (04) : 1301 - +
  • [20] Molecular analysis of toxigenic Vibrio cholerae O139 Bengal strains isolated in Bangladesh between 1993 and 1996: Evidence for emergence of a new clone of the Bengal vibrios
    Faruque, SM
    Ahmed, KM
    Siddique, AK
    Zaman, K
    AbdulAlim, ARM
    Albert, MJ
    [J]. JOURNAL OF CLINICAL MICROBIOLOGY, 1997, 35 (09) : 2299 - 2306