Ruthenium-catalyzed regioselective synthesis of 2-substituted indoles via ring-opening of epoxides by anilines

被引：30

作者：

Cho, CS ^{[1
]}

Kim, JH

Choi, HJ

Kim, TJ

Shim, SC

机构：

[1] Kyungpook Natl Univ, Ind Technol Res Inst, Taegu 702701, South Korea

[2] Kyungpook Natl Univ, Dept Ind Chem, Taegu 702701, South Korea

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 14期

基金：

新加坡国家研究基金会;

关键词：

anilines; epoxides; indoles; ring-opening; ruthenium catalyst;

D O I：

10.1016/S0040-4039(03)00396-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Anilines react with epoxides in dioxane at 180degreesC in the presence of a catalytic amount of a ruthenium catalyst along with tin(II) chloride to afford 2-substituted indoles in moderate to good yields. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：2975 / 2977

页数：3

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