Magnetic nanoparticles for drug delivery

被引:1296
作者
Arruebo, Manuel [1 ]
Fernandez-Pacheco, Rodrigo [1 ]
Ibarra, M. Ricardo [1 ]
Santamaria, Jesus [1 ]
机构
[1] Univ Zaragoza, INA, Zaragoza 50009, Spain
关键词
D O I
10.1016/S1748-0132(07)70084-1
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Controlled release of drugs from nanostructured functional materials, especially nanoparticles (NPs), is attracting increasing attention because of the opportunities in cancer therapy and the treatment of other ailments. The potential of magnetic NPs stems from the intrinsic properties of their magnetic cores combined with their drug loading capability and the biochemical properties that can be bestowed on them by means of a suitable coating. Here we review the problems and recent advances in the development of magnetic NPs for drug delivery, focusing particularly on the materials involved.
引用
收藏
页码:22 / 32
页数:11
相关论文
共 118 条
  • [61] Preparation of ultrafine Fe3O4 particles by precipitation in the presence of PVA at high pH
    Lee, J
    Isobe, T
    Senna, M
    [J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 1996, 177 (02) : 490 - 494
  • [62] Synthesis of amino-modified magnetite nanoparticles coated with Hepama-1 and radiolabeled with 188Re for bio-magnetically targeted radiotherapy
    Liang, Sheng
    Wang, Yongxian
    Zhang, Chunfu
    Liu, Xiuqing
    Liu, Zhenfeng
    Xu, Ronghui
    Yin, Duanzhi
    [J]. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, 2006, 269 (01) : 3 - 7
  • [63] Solid-state synthesis of monocrystalline iron oxide nanoparticle based ferrofluid suitable for magnetic resonance imaging contrast application
    Lu, Jun
    Yang, Shihe
    Ng, Ka Ming
    Su, Chia-Hao
    Yeh, Chen-Sheng
    Wu, Ya-Na
    Shieh, Dar-Bin
    [J]. NANOTECHNOLOGY, 2006, 17 (23) : 5812 - 5820
  • [64] Lubbe AS, 1996, CANCER RES, V56, P4694
  • [65] Lubbe AS, 1996, CANCER RES, V56, P4686
  • [66] Clinical applications of magnetic drug targeting
    Lübbe, AS
    Alexiou, C
    Bergemann, C
    [J]. JOURNAL OF SURGICAL RESEARCH, 2001, 95 (02) : 200 - 206
  • [67] Physiological aspects in magnetic drug-targeting
    Lübbe, AS
    Bergemann, C
    Brock, J
    McClure, DG
    [J]. JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 1999, 194 (1-3) : 149 - 155
  • [68] Plasma synthesis of carbon-iron magnetic nanoparticles and immobilization of doxorubicin for targeted drug delivery
    Ma, Y.
    Manolache, S.
    Denes, F.
    Vail, D.
    Thamm, D.
    Kurzman, I.
    [J]. JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE, 2006, 15 (03) : 376 - 382
  • [69] Plasma synthesis of carbon magnetic nanoparticles and immobilization of doxorubicin for targeted drug delivery
    Ma, YH
    Manolache, S
    Denes, FS
    Thamm, DH
    Kurzman, ID
    Vail, DM
    [J]. JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 2004, 15 (08) : 1033 - 1049
  • [70] Maassen S., 1993, STP Pharma Sci, V3, P11