Molecular epidemiology of astrovirus infection in Italian children with gastroenteritis

被引:32
作者
De Grazia, S
Giammanco, GM
Colomba, C
Cascio, A
Arista, S
机构
[1] Univ Palermo, Dipartimento Igiene & Microbiol, I-90127 Palermo, Italy
[2] Univ Palermo, Ist Patol Infett & Virol, Palermo, Italy
[3] Univ Messina, Clin Malattie Infett, Messina, Italy
关键词
astrovirus; children; diarrhoea; gastroenteritis; typing;
D O I
10.1111/j.1469-0691.2004.00995.x
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
A 1-year study involving 157 gastroenteritis samples was conducted to investigate the role of human astrovirus (HAstV) as a cause of gastroenteritis in Italian children aged < 2 years. The overall incidence of HAstV was 3.1%. Most cases occurred between March and May, and four of the five isolates were of the HAstV-1 type, the other being HAstV-3. Analysis of genetic variability showed that the three HAstV-1 isolates collected in 2000 clustered together, but separately from the 1999 isolate. The results indicated that HAstV should be considered as a potential diarrhoeal pathogen in Italian children.
引用
收藏
页码:1025 / 1029
页数:6
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