Monte Carlo characterization of clinical electron beams in transverse magnetic fields

被引:16
作者
Lee, MC [1 ]
Ma, CM [1 ]
机构
[1] Stanford Univ, Sch Med, Dept Radiat Oncol, Stanford, CA 94305 USA
关键词
D O I
10.1088/0031-9155/45/10/315
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Monte Carlo simulations were employed to study the characteristics of the electron beams of a clinical linear accelerator in the presence of 1.5 and 3.0 T transverse magnetic fields and to assess the possibility of using magnetic fields in conjunction with modulated electron radiation therapy (MERT). The starting depth of the magnetic field was varied over several centimetres. It was found that peak doses of as much as 2.7 times the surface dose could be achieved with a 1.5 T magnetic field. The magnetic field was shown to reduce the 80% and 20% dose drop-off distance by 50% to 80%. The distance between the 80% dose levels of the pseudo-Bragg peak induced by the magnetic field was found to be extremely narrow, generally less than 1 cm. However, by modulating the energy and intensity of the electron fields while simultaneously moving the magnetic field, a homogeneous dose distribution with low surface dose and a sharp dose fall-off was generated. Heterogeneities are shown to change the effective range of the electron beams, but not eliminate the advantages of a sharp depth-dose drop-off or high peak-to-surface dose ratio. This suggests the applicability of MERT with magnetic fields in heterogeneous media. The results of this study demonstrate the ability to use magnetic fields in MERT to produce highly desirable dose distributions.
引用
收藏
页码:2947 / 2967
页数:21
相关论文
共 23 条
[1]  
BIELAJEW AF, 1987, NUCL INSTRUM METH B, V18, P165
[2]   THE EFFECT OF STRONG LONGITUDINAL MAGNETIC-FIELDS ON DOSE DEPOSITION FROM ELECTRON AND PHOTON BEAMS [J].
BIELAJEW, AF .
MEDICAL PHYSICS, 1993, 20 (04) :1171-1179
[3]  
BIELAJEW AF, 1987, MONTE CARLO TRANSPOR, P4231
[4]   Electron beam modeling and commissioning for Monte Carlo treatment planning [J].
Jiang, SB ;
Kapur, A ;
Ma, CM .
MEDICAL PHYSICS, 2000, 27 (01) :180-191
[5]   Monte Carlo calculations of electron beam output factors for a medical linear accelerator [J].
Kapur, A ;
Ma, CM ;
Mok, EC ;
Findley, DO ;
Boyer, AL .
PHYSICS IN MEDICINE AND BIOLOGY, 1998, 43 (12) :3479-3494
[6]  
Lawson C.L., 1974, SOLVING LEAST SQUARE
[7]  
LEE MC, 2000, P 13 INT C US COMP R, P126
[8]  
LEE MC, 2000, IN PRESS MED PHYS, V27
[9]  
LEE MC, 2000, P WORLD C MED PYYS B
[10]   Energy- and intensity-modulated electron beams for radiotherapy [J].
Ma, CM ;
Pawlicki, T ;
Lee, MC ;
Jiang, SB ;
Li, JS ;
Deng, J ;
Yi, B ;
Mok, E ;
Boyer, AL .
PHYSICS IN MEDICINE AND BIOLOGY, 2000, 45 (08) :2293-2311