Coordination mode for turn-based phosphine ligands: the origin of selectivity in Pd catalysis

被引：12

作者：

Agarkov, A

Gilbertson, SR ^{[1
]}

机构：

[1] Univ Texas, Med Branch, Chem Biol Program Pharmacol & Toxicol, Galveston, TX 77555 USA

[2] Washington Univ, Dept Chem, St Louis, MO 63130 USA

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 01期

基金：

美国国家卫生研究院;

关键词：

phosphine; palladium; allylation; beta-turn;

D O I：

10.1016/j.tetlet.2004.10.096

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of experiments was performed to determine the nature of the catalyst in peptide-derived phosphine ligands. The selectivity of the catalyst system was determined with four ligands that are diastereomeric at the phosphine containing amino acid. Additionally, a series of monophosphine ligands was synthesized and screened to determine if the active catalysts are derived from a phosphine-amide complex. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：181 / 183

页数：3

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