A wireless implantable multichannel digital neural recording system for a micromachined sieve electrode

被引:146
作者
Akin, T [1 ]
Najafi, K
Bradley, RM
机构
[1] Middle E Tech Univ, Dept Elect & Elect Engn, TR-06531 Ankara, Turkey
[2] Univ Michigan, Dept Elect Engn & Comp Sci, Ctr Integrated Sensors & Circuits, Ann Arbor, MI 48109 USA
[3] Univ Michigan, Sch Dent, Dept Biol & Mat Sci, Ann Arbor, MI 48109 USA
基金
美国国家卫生研究院;
关键词
biomedical sensor; interface circuit; RF circuit;
D O I
10.1109/4.654942
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
This paper reports the development of an implantable, fully integrated, multichannel peripheral neural recording system, which is powered and controlled using an RF telemetry link, The system allows recording of +/-500 mu V neural signals from axons regenerated through a micromachined silicon sieve electrode, These signals are amplified using on-chip 100 Hz to 3.1 kHz bandlimited amplifiers, multiplexed, and digitized with a low-power (<2 mW), moderate speed (8 mu s/b) current-mode 8-b analog-to-digital converter (ADC), The digitized signal is transmitted to the outside world using a passive RF telemetry link, The circuit is implemented using a bipolar CMOS process, The signal processing CMOS circuitry dissipates only 10 mW of power from a 5-V supply while operating at 2 MHz and consumes 4 x 4 mm(2) of area, The overall circuit including the RF interface circuitry contains over 5000 transistors, dissipates 90 mW of power, and consumes 4 x 6 mm(2) of area.
引用
收藏
页码:109 / 118
页数:10
相关论文
共 18 条
[1]   A MICROMACHINED SILICON SIEVE ELECTRODE FOR NERVE REGENERATION APPLICATIONS [J].
AKIN, T ;
NAJAFI, K ;
SMOKE, RH ;
BRADLEY, RM .
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1994, 41 (04) :305-313
[2]  
Akin T., 1995, 8th International Conference on Solid-State Sensors and Actuators and Eurosensors IX. Digest of Technical Papers (IEEE Cat. No.95TH8173), P51
[3]  
AKIN T, 1990, SOL STAT SENS ACT WO, P145
[4]  
ALLEN HV, 1979, BIOTELEM PAT MON, V6, P147
[5]   A MONOLITHIC SIGNAL PROCESSOR FOR A NEUROPHYSIOLOGICAL TELEMETRY SYSTEM [J].
DORMAN, MG ;
PRISBE, MA ;
MEINDL, JD .
IEEE JOURNAL OF SOLID-STATE CIRCUITS, 1985, 20 (06) :1185-1193
[6]   MUTUAL INDUCTANCE OF AIR-CORED COILS - EFFECT ON DESIGN OF RADIO-FREQUENCY COUPLED IMPLANTS [J].
FLACK, FC ;
JAMES, ED ;
SCHLAPP, DM .
MEDICAL & BIOLOGICAL ENGINEERING, 1971, 9 (02) :79-&
[7]  
GALBRAITH DC, 1984, THESIS STANDORD U
[8]   AN IMPLANTABLE CMOS CIRCUIT INTERFACE FOR MULTIPLEXED MICROELECTRODE RECORDING ARRAYS [J].
JI, J ;
WISE, KD .
IEEE JOURNAL OF SOLID-STATE CIRCUITS, 1992, 27 (03) :433-443
[9]   DESIGN CONSIDERATIONS FOR A HIGH-PERFORMANCE 3-MUM CMOS ANALOG STANDARD-CELL LIBRARY [J].
LABER, CA ;
RAHIM, CF ;
DREYER, SF ;
UEHARA, GT ;
KWOK, PT ;
GRAY, PR .
IEEE JOURNAL OF SOLID-STATE CIRCUITS, 1987, 22 (02) :181-189
[10]   INTRACRANIAL-PRESSURE TELEMETRY SYSTEM USING SEMICUSTOM INTEGRATED-CIRCUITS [J].
LEUNG, AM ;
KO, WH ;
SPEAR, TM ;
BETTICE, JA .
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1986, 33 (04) :386-395