Indomethacin for prevention of heterotopic ossification after hip arthroplasty - A randomized comparison between 4 and 8 days of treatment

被引:27
作者
Dorn, U [1 ]
Grethen, C [1 ]
Effenberger, H [1 ]
Berka, H [1 ]
Ramsauer, T [1 ]
Drekonja, T [1 ]
机构
[1] Salzburg Gen Hosp, Dept Orthoped, A-5020 Salzburg, Austria
来源
ACTA ORTHOPAEDICA SCANDINAVICA | 1998年 / 69卷 / 02期
关键词
D O I
10.3109/17453679809117607
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
In a randomized, parallel group study, we evaluated the efficacy of a 4-day versus an 8-day course of indomethacin (50 mg, 3 times per day), given as prophylaxis against heterotopic ossification after cementless total hip arthroplasty in 209 patients with arthrosis. Patients receiving the prophylaxis for 8 days had less (p = 0.03) severe heterotopic bone formation.
引用
收藏
页码:107 / 110
页数:4
相关论文
共 35 条
[31]   THE USE OF INDOMETHACIN TO PREVENT THE FORMATION OF HETEROTOPIC BONE AFTER TOTAL HIP-REPLACEMENT - A RANDOMIZED, DOUBLE-BLIND CLINICAL-TRIAL [J].
SCHMIDT, SA ;
KJAERSGAARDANDERSEN, P ;
PEDERSEN, NW ;
KRISTENSEN, SS ;
PEDERSEN, P ;
NIELSEN, JB .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1988, 70A (06) :834-838
[32]  
SOBALLE K, 1988, CLIN ORTHOP RELAT R, V228, P57
[33]  
TORNKVIST H, 1985, CLIN ORTHOP RELAT R, P264
[34]   HETEROTOPIC BONE-FORMATION PREVENTED BY DICLOFENAC - PROSPECTIVE-STUDY OF 100 HIP ARTHROPLASTIES [J].
WAHLSTROM, O ;
RISTO, O ;
DJERF, K ;
HAMMERBY, S .
ACTA ORTHOPAEDICA SCANDINAVICA, 1991, 62 (05) :419-421
[35]  
WURNIG C, 1992, ACTA ORTHOP SCAND, V63, P628