Mapping the cancer genome - Pinpointing the genes involved in cancer will help chart a new course across the complex landscape of human malignancies

被引：143

作者：

Collins, Francis S. ^{[1
]}

Barker, Anna D. ^{[1
]}

机构：

[1] NCI, Adv Technol & Strateg Partnerships, Bethesda, MD 20892 USA

来源：

SCIENTIFIC AMERICAN | 2007年 / 296卷 / 03期

关键词：

D O I：

10.1038/scientificamerican0307-50

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Pinpointing the genes involved in cancer will help chart a new course across the complex landscape of human malignancies. Changes in the structure or activity of genes underlie the malignant behavior of many cancer cells. The Cancer Genome Atlas is a monumental initiative to eventually identify all the genetic alterations in different forms of cancer so that gene changes driving disease can be targeted directly. Identification of the genes involved is already advancing diagnosis and treatment.

引用

页码：50 / 57

页数：8

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