The fight of viruses against apoptosis

被引：157

作者：

Tschopp, J

Thome, M

Hofmann, K

Meinl, E

机构：

[1] Univ Lausanne, Inst Biochem, CH-1066 Epalinges, Switzerland

[2] Swiss Inst Expt Canc Res, BIL Res Ctr, CH-1066 Epalinges, Switzerland

[3] Inst Klin & Mol Virol, D-91054 Erlangen, Germany

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1998年 / 8卷 / 01期

关键词：

D O I：

10.1016/S0959-437X(98)80066-X

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The induction of apoptosis of virus-infected cells is an important host defense mechanism against invading pathogens. Some viruses express anti-apoptotic proteins that efficiently block apoptosis induced by death receptors or in response to stress signaled through mitochondria. Viral interference with host cell apoptosis leads to enhanced viral replication and may promote cancer.

引用

页码：82 / 87

页数：6

共 58 条

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