An improved synthesis of 6-deoxyhalo cyclodextrins via halomethylenemorpholinium halides Vilsmeier-Haack type reagents

被引：23

作者：

Chmurski, K

Defaye, J

机构：

[1] CNRS,DEPT PHARMACOCHIM MOL,F-38243 MEYLAN,FRANCE

[2] UNIV GRENOBLE 1,F-38243 MEYLAN,FRANCE

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 42期

关键词：

cyclodextrins; cyclomaltooligosaccharides; bromomethylenemorpholinium bromide; chloromethylenemorpholinium chloride; per(6-deoxyhalo) cyclodextrins;

D O I：

10.1016/S0040-4039(97)10019-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Per(6-bromo-6-deoxy)cyclomalto-hexaose, -heptaose, and -octaose and the corresponding per(6-chloro-6-deoxy) derivatives were prepared in high yield by reaction of bromomethylenemorpholinium bromide or chloromethylenemorpholinium chloride, respectively, with cyclomaltohexaose, cyclomaltoheptaose and cyclomaltooctaose in dimethylformamide. (C) 1997 Elsevier Science Ltd.

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收藏

页码：7365 / 7368

页数：4

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