Is TfR2 the iron sensor?

被引:9
作者
Ganz, T [1 ]
机构
[1] David Geffen Sch Med, Los Angeles, CA USA
关键词
D O I
10.1182/blood-2004-09-3664
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The liver has a central role in regulating the absorption of iron from the diet and the release of stored iron. How does the liver monitor the iron requirements of erythropoiesis? Two articles provide evidence that hepatic transferrin receptor 2 (TfRZ) molecules sense the concentration of diferric transferrin in plasma.
引用
收藏
页码:3839 / 3840
页数:2
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