Endothelin receptor antagonists: which are the therapeutic perspectives in renal diseases?

被引：14

作者：

Benigni, A ^{[1
]}

Remuzzi, G ^{[1
]}

机构：

[1] Mario Negri Inst Pharmacol Res, I-24125 Bergamo, Italy

来源：

NEPHROLOGY DIALYSIS TRANSPLANTATION | 1998年 / 13卷 / 01期

关键词：

D O I：

10.1093/ndt/13.1.5

中图分类号：

R3 [基础医学]; R4 [临床医学];

学科分类号：

1001 ; 1002 ; 100602 ;

摘要：

Since the discovery of endothelin peptides, much interdisciplinary research looked into their unique profile as powerful and long-lasting vasoconstrictors and mitogens. On account of the renal vasculature's sensitivity to endothelin-l and the peptide's various effects on the kidney, the role of endothelin-l in the control of kidney function has attracted particular attention.

引用

页码：5 / 7

页数：3

共 14 条

[1] Benigni A, 1995, Curr Opin Nephrol Hypertens, V4, P349, DOI 10.1097/00041552-199507000-00011
[2] The renoprotective potential of endothelin receptor antagonists
Benigni, A
Remuzzi, G
[J]. EXPERT OPINION ON THERAPEUTIC PATENTS, 1997, 7 (02) : 139 - 149
[3] Endothelin-1 transgenic mice develop glomerulosclerosis, interstitial fibrosis, and renal cysts but not hypertension
Hocher, B
ThoneReineke, C
Rohmeiss, P
Schmager, F
Slowinski, T
Burst, V
Siegmund, F
Quertermous, T
Bauer, C
Neumayer, HH
Schleuning, WD
Theuring, F
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1997, 99 (06) : 1380 - 1389
[4] THE HUMAN ENDOTHELIN FAMILY - 3 STRUCTURALLY AND PHARMACOLOGICALLY DISTINCT ISOPEPTIDES PREDICTED BY 3 SEPARATE GENES
INOUE, A
YANAGISAWA, M
KIMURA, S
KASUYA, Y
MIYAUCHI, T
GOTO, K
MASAKI, T
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (08) : 2863 - 2867
[5] ENDOTHELIN RECEPTOR SUBTYPE-B MEDIATES AUTOINDUCTION OF ENDOTHELIN-1 IN RAT MESANGIAL CELLS
IWASAKI, S
HOMMA, T
MATSUDA, Y
KON, V
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (12) : 6997 - 7003
[6] Endothelins in the normal and diseased kidney
Kohan, DE
[J]. AMERICAN JOURNAL OF KIDNEY DISEASES, 1997, 29 (01) : 2 - 26
[7] Nabokov A, 1996, NEPHROL DIAL TRANSPL, V11, P514
[8] AN ENDOTHELIN-1 MEDIATED AUTOCRINE GROWTH LOOP INVOLVED IN HUMAN RENAL TUBULAR REGENERATION
ONG, ACM
JOWETT, TP
FIRTH, JD
BURTON, S
KARET, FE
FINE, LG
[J]. KIDNEY INTERNATIONAL, 1995, 48 (02) : 390 - 401
[9] EVIDENCE FOR ENDOTHELIN-INDUCED RENAL VASOCONSTRICTION INDEPENDENT OF ETA RECEPTOR ACTIVATION
POLLOCK, DM
OPGENORTH, TJ
[J]. AMERICAN JOURNAL OF PHYSIOLOGY, 1993, 264 (01): : R222 - R226
[10] ENDOTHELIN-1 STIMULATES ITS OWN SYNTHESIS IN HUMAN ENDOTHELIAL-CELLS
SAIJONMAA, O
NYMAN, T
FYHRQUIST, F
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1992, 188 (01) : 286 - 291

← 1 2 →