Prions: Portable prion domains

被引：19

作者：

Wickner, RB ^{[1
]}

Taylor, KL ^{[1
]}

Edskes, HK ^{[1
]}

Maddelein, ML ^{[1
]}

机构：

[1] NIDDK, Lab Biochem & Genet, NIH, Bethesda, MD 20892 USA

来源：

CURRENT BIOLOGY | 2000年 / 10卷 / 09期

关键词：

D O I：

10.1016/S0960-9822(00)00460-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Self-propagating abnormal proteins, prions, have been identified in yeast; asparagine/glutamine rich 'prion domains' within these proteins can inactivate the linked functional domains; new prion domains and reporters have been used to make 'synthetic prions', leading to discoveries of new natural prions.

引用

页码：R335 / R337

页数：3

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