New benzylpiperazine derivatives bearing mono- and bis-dialky 1 2,4-triazoles substituted

被引:8
作者
Al-Soud, YA [2 ]
Qalalweh, MNA
Al-Sa'doni, HH
Al-Masoudi, NA
机构
[1] Univ Konstanz, Fachbereich Chim, D-78457 Constance, Germany
[2] Univ Al Al Bayt, Coll Sci, Dept Chem, Al Mafraq, Iran
关键词
D O I
10.1002/hc.20061
中图分类号
O6 [化学];
学科分类号
0703 [化学];
摘要
Cycloaddition of the 1-aza-2-azoniaallenes 3 with p-cyanobenzyl chlorides afforded, after spontaneous rearrangement, the 1,5-dialkyl-3-[4-chloromethyl)phenyl]-1H-[1,2,4]-triazoles 6. A series of 1,5-dialkyl-1H-[1,2,4]-triazol-3-yl)benzylpiperazines 7 and 8 were prepared from direct condensation of 6 with piperazine and N-methylpiperazine, respectively. The structures of the newly synthesized products were identified by 2D NMR spectroscopy. (C) 2005 Wiley Periodicals, Inc.
引用
收藏
页码:28 / 32
页数:5
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