Quinone approaches toward the synthesis of aflatoxin B2

被引：17

作者：

Noland, WE ^{[1
]}

Kedrowski, BL ^{[1
]}

机构：

[1] Univ Minnesota, Dept Chem, Minneapolis, MN 55455 USA

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 14期

关键词：

D O I：

10.1021/ol006014r

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Quinones bearing electron withdrawing groups can serve as useful precursors to furobenzofuran ring systems through their reaction with 2,3-dihydrofuran. Formal racemic and stereoselective syntheses of the fungal metabolite aflatoxin B-2 are described that utilize this approach to construct the tricyclic ABC-ring core of the molecule.

引用

页码：2109 / 2111

页数：3